Collection: Aspen

Moducare® by Aspen is a mixture of sitosterol (BSS) and its glucoside sitosterolin (BSSG) in a 100:1 ratio. This formulation was originally marketed in 1974 in Germany, after its beneficial effect in the treatment of benign prostate hypertrophy (BPH) had been established. Two years later, the same BSS/BSSG mixture was marketed in a product for rheumatoid arthritis.

In 1989, Professor Patrick Bouic and his colleagues at the Medical School of the University of Stellenbosch, Capetown, South Africa discovered that both sitosterol and sitosterolin have an immune modulating effect. Their findings, which were published in the Int J of Immunopharmacology 1996, 18, 693-700, eventually resulted in the patented product called Moducare®.

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