PRODUCT DESCRIPTION

A perfect complement of curcumin and turmeric supplementation that delivers the best of modern science while overcoming the limitations of curcumin absorption. Further enhanced with the wisdom of nature and turmeric in its complete form. For the first time this unique approach combines market-leading BCM-95™ curcumin with specialised whole organic turmeric extracts that generates the full spectrum of turmeric terpenoids and bioactives. Allowing your body to efficiently deliver high levels of bioactive curcumin and whole turmeric into the blood stream via a convenient single capsule.

RECOMMENDED USAGE

Adults and children over 12 years: First week take 2 capsules per day with food. After the first week, take 1 to 2 capsules per day with food or as recommended by your healthcare professional.

COMPOSITION

OTHER INGREDIENTS

Brown rice flour, magnesium stearate and silicon dioxide in a clear vegetable capsule.

DOES NOT CONTAIN

Sugar.

STORAGE

Store or at below 25°. Keep in outer container until required for use. Protect from light and moisture.

PRODUCT FORM

Capsule

WARNINGS/CONTRAINDICATION

Keep out of reach of children.

• Patients with hypersensitivity to turmeric, curcumin, or any of the other components of the formulation (see Section 2 Qualitative and Quantitative Composition and Section 6.1 List of excipients)
• Pregnancy, especially within the first trimester, since NATROCEUTICS CURCUMIN may cause uterine contractions (see Section 4.6 Fertility, pregnancy, and lactation).
• Caution is advised when NATROCEUTICS CURCUMIN is recommended to people who have been diagnosed with cholelithiasis or gall bladder disease, since it may cause contractions of the gallbladder or bile ducts. NATROCEUTICS CURCUMIN should be discontinued if epigastric pain (which may radiate to the right shoulder) and/or nausea develop.
• NATROCEUTICS CURCUMIN may have an antiplatelet effect (see Section 4.5 Interaction with other medicines and other forms of interaction). Caution is therefore required in patients with bleeding disorders. Such users should be advised to stop taking NATROCEUTICS CURCUMIN if they develop bruises, nose bleeds or bleeding from the gums.
• Patients with gastro-oesophageal reflux disease (GORD) or a history of gastric ulcers should be advised that NATROCEUTICS CURCUMIN may cause gastrointestinal side effects, including dyspepsia and acid reflux. Advise these patients to consult their treating doctor prior to use. Gastrointestinal side effects may be reduced or prevented by taking NATROCEUTICS CURCUMIN with or immediately after meals and never on an empty stomach.
• NATROCEUTICS CURCUMIN should be used with caution by people trying to conceive. In vitro and animal research indicate possible antifertility effects affecting sperm production (see Section 4.6 Fertility, pregnancy, and lactation).
• NATROCEUTICS CURCUMIN may lower blood glucose levels in patients with type 2 diabetes. Inform patients with diabetes to use NATROCEUTICS CURCUMIN carefully. They should monitor blood glucose levels closely, especially at the beginning of supplementation or should they discontinue NATROCEUTICS CURCUMIN after chronic use. It may be necessary to adjust the dosage of their antidiabetic medicines (see Section 4.5 Interaction with other medicines and other forms of interaction).
• Patients scheduled for elective surgery should be advised to discontinue NATROCEUTICS CURCUMIN at least 2 weeks prior to the procedure due its potential antiplatelet and hypoglycaemic effects.
• ANTICOAGULANT/ANTIPLATELET MEDICINES NATROCEUTICS CURCUMIN may have antiplatelet effects and may increase the risk of bleeding if used in combination with anticoagulant or antiplatelet medicines. These patients should be advised to stop taking NATROCEUTICS CURCUMIN and report to their doctor or healthcare professional if they develop bruises, nose bleeds or bleeding from the gums (see Section 4.4 Special warnings and precautions for use). In addition, patients taking warfarin should have their INR checked, especially at the beginning or end of supplementation with NATROCEUTICS CURCUMIN
• ANTIDIABETIC MEDICINES NATROCEUTICS CURCUMIN may increase the risk of low blood glucose levels in patients treated with antidiabetic medicines and careful monitoring of blood glucose levels is required, especially at the onset of supplementation (see Section 4.4 Special warnings and precautions for use). Should NATROCEUTICS CURCUMIN be used over the long-term, dosage adjustments of antidiabetic medicines may be required. Examples of antidiabetic medicines include, but are not limited to, glimepiride, insulin, metformin, pioglitazone, and others.
• SULFASALAZINE NATROCEUTICS CURCUMIN may increase blood levels of sulfasalazine with the potential to increase adverse events from sulfasalazine. Advise individuals who take sulfasalazine and NATROCEUTICS CURCUMIN concurrently to be watchful for any increase in sulfasalazine side effects and to report these to their doctor immediately. For more information on the side effects of sulfasalazine, patients should refer to its patient leaflet
• ANTICOAGULANT/ANTIPLATELET HERBS AND SUPPLEMENTS Due to its antiplatelet effects, caution is advised when NATROCEUTICS CURCUMIN is used in combination with herbs that may affect platelet aggregation, such as angelica, clove, danshen, garlic, ginger, ginkgo, Panax ginseng, red clover, willow, and others.
• Due to its hypoglycaemic potential, caution is advised when NATROCEUTICS CURCUMIN is combined with the following herbs or supplements that are known to reduce blood glucose levels: alpha-lipoic acid, bitter melon, chromium, devil’s claw, fenugreek, garlic, guar gum, horse chestnut, Panax ginseng, psyllium, Siberian ginseng, and others.
• Pregnancy There is evidence that turmeric, when used in medicinal amounts, may stimulate menstrual flow and cause contractions of the uterus. The use of NATROCEUTICS CURCUMIN is contraindicated in pregnancy (see Section 4.3 Contraindications).
• Lactation There is insufficient reliable information about the safety of NATROCEUTICS CURCUMIN during lactation. Use during lactation is not advised.
• Fertility Animal and in vitro research suggests that curcumin may decrease sperm motility and density, cause degenerative changes in the seminiferous tubules, reduce luteinizing hormone (LH)-stimulated production of testosterone in adult Leydig cells, and reduce fertility when administered orally. Until more is known, NATROCEUTICS CURCUMIN should be used with caution in individuals who are trying to conceive.
• Effects on ability to drive and use machines No studies on the effect on the ability to drive and use machines have been performed. Given its side effect profile, it is unlikely that NATROCEUTICS CURCUMIN will affect the ability to drive or operate machinery.
• Turmeric is generally well tolerated when taken orally. Adverse events are mostly gastro-intestinal in nature. The most common side effects include constipation, dyspepsia, diarrhoea, distension, gastroesophageal reflux, nausea, vomiting and others. In clinical research, the frequency of these adverse events is similar to that of placebo.